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Table 2 Patients characteristics at first visit and week 24 in sustained remission for patients in sustained clinical remission of 24 weeks or longer according to the DAS28 and SDAI definition of remission

From: Physical function continues to improve when clinical remission is sustained in rheumatoid arthritis patients

 

DAS28 REM

SDAI REM

 

Week 0

Week 24

p

Week 0

Week 24

p

Disease activity score using 28-joint counts including CRP (DAS28)

2.1 ± 0.3 (1.21–2.6)

1.9 ± 0.3 (1.01–2.59)

P <0.01

1.8 ± 0.28 (1.21–2.72)

1.7 ± 0.2 (1.21–2.72)

P <0.01

Simplified disease activity index (SDAI)

4.3 ± 2.8 (0.3–16.1)

3.2 ± 2.5 (0.1–18.2)

P <0.01

1.9 ± 0.9 (0.1–3.3)

1.3 ± 0.8 (0.1–3.24)

P <0.01

Health assessment questionnaire (HAQ)

0.28 ± 0.4 (0–2.25)

0.20 ± 0.4 (0–1.92)

P <0.01

0.15 ± 0.3 (0–2.25)

0.11 ± 0.3 (0–1.75)

P <0.01

Swollen joint count 28 joints (SJC28)

1.3 ± 2.2 (0–15)

0.8 ± 2.0 (0–17)

P <0.01

0.3 ± 0.5 (0–2)

0.2 ± 0.4 (0–2)

P <0.01

Tender joint count 28 joints (TJC28)

0.4 ± 0.7 (0–3)

0.2 ± 0.5 (0–3)

P <0.01

0.2 ± 0.5 (0–2)

0.1 ± 0.4 (0–2)

P <0.01

Visual analogue scale for pain (VAS pain in mm)

8.8 ± 10.9 (0–80)

6.9 ± 8.5 (0–64)

P <0.01

4.4 ± 6.1 (0–53)

3.0 ± 4.0 (0–24)

P <0.01

Patient global assessment of disease activity (PGA in mm)

11 ± 11.8 (0–70)

8.8 ± 9.6 (0–57)

P <0.01

4.5 ± 5.4 (0–27)

3.5 ± 4.9 (0–30)

P <0.01

Evaluator global assessment of disease activity (EGA in mm)

10.2 ± 10.3 (0–92)

7.7 ± 8.9 (0–93)

P <0.01

4.4 ± 4.7 (0–24)

3.1 ± 3.7 (0–17)

P <0.01

C-reactive protein (CRP, mg/dL)

0.50 ± 0.6 (0.1–9.4)

0.52 ± 0.5 (0.1–4.3)

P = 0.46

0.49 ± 0.4 (0.1–2.92)

0.50 ± 0.4 (0.1–3.8)

P = 0.69

  1. Values are given for means ± standard deviation, significant differences were detected, using Student’s t test. Values in parentheses depict ranges. Differences between DAS28 REM and SDAI REM were significant at p <0.01 for all variables and time points except for CRP. REM remission