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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Rheumatoid factor, not antibodies against citrullinated proteins, is associated with baseline disease activity in rheumatoid arthritis clinical trials

Fig. 2

Disease activity distributions for the simplified disease activity index (SDAI) at baseline according to rheumatoid factor (RF) or anti-citrullinated peptide antibodies (ACPAs) or both. Probability plots of levels of disease activity according to the SDAI. a, c, e Distributions of baseline SDAI values by RF status (negative versus high positive) in patients matched for ACPA, age, and duration (higher disease activity in RF-positive patients; overall P = 0.0067). b, d, f Distributions of baseline SDAI values by ACPA status (negative versus highly positive) in patients matched for RF levels, age, and duration of RA (higher disease activity in ACPA-negative patients; overall P = 0.054). Data are separated by trials for IMAGE trial (a, b), GO-BEFORE (c, d), and combined GO-FORWARD+GO-AFTER (e, f)

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Arthritis Research & Therapy

ISSN: 1478-6362

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