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Table 1 Clinical characteristics of patients

From: Association of CXCL10 and CXCL13 levels with disease activity and cutaneous manifestation in active adult-onset Still’s disease

 

AOSD (n = 39)

RA (n = 32)

HC (n = 40)

Age (years)

42.2 ± 15.8

44.7 ± 8

37.7± 8.7

Gender (F/M)

36/3

27/5

35/5

Fever

34 (87.2)

  

Sore throat

21 (53.8)

  

Skin rash

32 (82.1)

  

Lymphadenopathy

14 (35.9)

  

Splenomegaly

10 (25.6)

  

Hepatomegaly

5 (12.8)

  

Pericarditis

6 (15.4)

  

Arthritis

24 (61.5)

31 (96.9)

 

Hemoglobin, g/dL

11 ± 1.8

12.8 ± 1.4

 

Leukocytes, /μL

13,130 ± 5,015

7,613 ± 3,061

 

Platelets, x103/μL

316.2 ± 117.9

267.9 ± 78.9

 

Ferritin, ng/mL

7,229.7 ± 13,091.1

  

ESR, mm/h

64.6 ± 29.3

31.9 ± 24.7

 

CRP, mg/dL

8.53 ± 6.68

1.07 ± 2.41

 

AST/ALT, mg/dL

55.8 ± 42.8/54.4 ± 46.7

25.2 ± 10.3/23.3 ± 17.4

 

Bilirubin, mg/dL

0.67 ± 0.8

0.58 ± 0.2

 

Albumin, g/dL

3.74 ± 0.64

4.48 ± 0.32

 

ANA positivity

6 (15.4)

9 (28.1)

 

RF positivity

4 (10.3)

29 (90.6)

 

Systemic score

4.79 ± 1.81

  

DAS-28

 

3.91 ± 1.2

 
  1. AOSD adult onset Still’s disease, RA rheumatoid arthritis, HC healthy controls, ESR erythrocyte sedimentation rate, CRP C-reactive protein, AST aspartate transaminase, ALT alanine transaminase, ANA antinuclear antibody, RF rheumatoid factor. DAS-28, disease activity score including 28 joints. All values are presented as numbers (with percentages) or means ± standard deviations. The systemic scoring system of Pouchot et al. [28] assigns a score from 0 to 12 with 1 point for each of the following manifestations: fever, typical rash, pleuritis, pneumonia, pericarditis, hepatomegaly or abnormal liver function test data, splenomegaly, lymphadenopathy, leukocytosis ≥ 15,000/mm2, sore throat, myalgia, and abdominal pain