| |
AOSD (n = 39)
|
RA (n = 32)
|
HC (n = 40)
|
|---|
|
Age (years)
|
42.2 ± 15.8
|
44.7 ± 8
|
37.7± 8.7
|
|
Gender (F/M)
|
36/3
|
27/5
|
35/5
|
|
Fever
|
34 (87.2)
| | |
|
Sore throat
|
21 (53.8)
| | |
|
Skin rash
|
32 (82.1)
| | |
|
Lymphadenopathy
|
14 (35.9)
| | |
|
Splenomegaly
|
10 (25.6)
| | |
|
Hepatomegaly
|
5 (12.8)
| | |
|
Pericarditis
|
6 (15.4)
| | |
|
Arthritis
|
24 (61.5)
|
31 (96.9)
| |
|
Hemoglobin, g/dL
|
11 ± 1.8
|
12.8 ± 1.4
| |
|
Leukocytes, /μL
|
13,130 ± 5,015
|
7,613 ± 3,061
| |
|
Platelets, x103/μL
|
316.2 ± 117.9
|
267.9 ± 78.9
| |
|
Ferritin, ng/mL
|
7,229.7 ± 13,091.1
| | |
|
ESR, mm/h
|
64.6 ± 29.3
|
31.9 ± 24.7
| |
|
CRP, mg/dL
|
8.53 ± 6.68
|
1.07 ± 2.41
| |
|
AST/ALT, mg/dL
|
55.8 ± 42.8/54.4 ± 46.7
|
25.2 ± 10.3/23.3 ± 17.4
| |
|
Bilirubin, mg/dL
|
0.67 ± 0.8
|
0.58 ± 0.2
| |
|
Albumin, g/dL
|
3.74 ± 0.64
|
4.48 ± 0.32
| |
|
ANA positivity
|
6 (15.4)
|
9 (28.1)
| |
|
RF positivity
|
4 (10.3)
|
29 (90.6)
| |
|
Systemic score
|
4.79 ± 1.81
| | |
|
DAS-28
| |
3.91 ± 1.2
| |
-
AOSD adult onset Still’s disease, RA rheumatoid arthritis, HC healthy controls, ESR erythrocyte sedimentation rate, CRP C-reactive protein, AST aspartate transaminase, ALT alanine transaminase, ANA antinuclear antibody, RF rheumatoid factor. DAS-28, disease activity score including 28 joints. All values are presented as numbers (with percentages) or means ± standard deviations. The systemic scoring system of Pouchot et al. [28] assigns a score from 0 to 12 with 1 point for each of the following manifestations: fever, typical rash, pleuritis, pneumonia, pericarditis, hepatomegaly or abnormal liver function test data, splenomegaly, lymphadenopathy, leukocytosis ≥ 15,000/mm2, sore throat, myalgia, and abdominal pain
