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Table 1 Clinical characteristics of patients

From: Association of CXCL10 and CXCL13 levels with disease activity and cutaneous manifestation in active adult-onset Still’s disease

  AOSD (n = 39) RA (n = 32) HC (n = 40)
Age (years) 42.2 ± 15.8 44.7 ± 8 37.7± 8.7
Gender (F/M) 36/3 27/5 35/5
Fever 34 (87.2)   
Sore throat 21 (53.8)   
Skin rash 32 (82.1)   
Lymphadenopathy 14 (35.9)   
Splenomegaly 10 (25.6)   
Hepatomegaly 5 (12.8)   
Pericarditis 6 (15.4)   
Arthritis 24 (61.5) 31 (96.9)  
Hemoglobin, g/dL 11 ± 1.8 12.8 ± 1.4  
Leukocytes, /μL 13,130 ± 5,015 7,613 ± 3,061  
Platelets, x103/μL 316.2 ± 117.9 267.9 ± 78.9  
Ferritin, ng/mL 7,229.7 ± 13,091.1   
ESR, mm/h 64.6 ± 29.3 31.9 ± 24.7  
CRP, mg/dL 8.53 ± 6.68 1.07 ± 2.41  
AST/ALT, mg/dL 55.8 ± 42.8/54.4 ± 46.7 25.2 ± 10.3/23.3 ± 17.4  
Bilirubin, mg/dL 0.67 ± 0.8 0.58 ± 0.2  
Albumin, g/dL 3.74 ± 0.64 4.48 ± 0.32  
ANA positivity 6 (15.4) 9 (28.1)  
RF positivity 4 (10.3) 29 (90.6)  
Systemic score 4.79 ± 1.81   
DAS-28   3.91 ± 1.2  
  1. AOSD adult onset Still’s disease, RA rheumatoid arthritis, HC healthy controls, ESR erythrocyte sedimentation rate, CRP C-reactive protein, AST aspartate transaminase, ALT alanine transaminase, ANA antinuclear antibody, RF rheumatoid factor. DAS-28, disease activity score including 28 joints. All values are presented as numbers (with percentages) or means ± standard deviations. The systemic scoring system of Pouchot et al. [28] assigns a score from 0 to 12 with 1 point for each of the following manifestations: fever, typical rash, pleuritis, pneumonia, pericarditis, hepatomegaly or abnormal liver function test data, splenomegaly, lymphadenopathy, leukocytosis ≥ 15,000/mm2, sore throat, myalgia, and abdominal pain