Arthritis Research & Therapy

Table 1 24-h proteinuria

From: Early treatment with hydroxychloroquine prevents the development of endothelial dysfunction in a murine model of systemic lupus erythematosus

Age, wk	Group	Mean	SD	Group	Mean	SD	Group	Mean	SD
8–12	NZ	0.30	0.1	NZ_HCQ	0.22	0.02	Ctrl	1.35	1.23
18	NZ	0.56	0.44	NZ_HCQ	0.18	0.40	Ctrl	0.46	0.42
20	NZ	3.5^a	2.7	NZ_HCQ	0.43	0.15	Ctrl	0.78	0.6
24	NZ	4.06	2.8	NZ_HCQ	0.23	0.10	Ctrl	0.34	0.40
30	NZ	4.9	2.2	NZ_HCQ	0.35	0.34	Ctrl	0.27	0.07
36	NZ	12.5	3.5	NZ_HCQ	12.18^b	6.3	Ctrl	1.083	0.50

Ctrl untreated control, NZ female NZB/W F1, NZ _HCQ NZB/W F1 mice with systemic lupus erythematosus treated with hydroxychloroquine, SD standard deviation
Data are presented in milligrams per 24 h
^a P < 0.05 at 20 weeks vs. 18 weeks
^b P < 0.05 at 36 weeks vs. 30 weeks

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ISSN: 1478-6362

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