From: Serum hyaluronic acid concentration predicts the progression of joint space narrowing in normal knees and established knee osteoarthritis – a five-year prospective cohort study
Baseline
Endpoint
Development/progression
KL grade
Number
0/1
2
3
4
0, 1
323
194
96
33
129
91
44
43
47
28
14
Total
444
140
90
20
190