Table 1 Incident cases of rheumatoid arthritis and controls: characteristics and lipid levels, stratified by sex
From: High serum cholesterol predicts rheumatoid arthritis in women, but not in men: a prospective study
All | Women | Men | ||||
|---|---|---|---|---|---|---|
Cases | Controls | Cases | Controls | Cases | Controls | |
Number | 290 | 1160 | 139 | 556 | 151 | 604 |
Age at inclusion | 47.1 (7.1) | 47.1 (7.1) | 49.3 (7.4) | 49.3 (7.4) | 45.5 (6.2) | 45.5 (6.2) |
Years; mean (SD) | ||||||
Time from inclusion to RA diagnosis | 12 (8–18) | NA | 11 (7–16) | NA | 13 (9–19) | NA |
Years; median (IQR) | ||||||
Age at diagnosis | 59.9 (8.8; 30–81) | NA | 60.8 (8.4; 30–76) | NA | 59.1 (9.0; 40–81) | NA |
Years; mean (SD; range) | ||||||
RF-positive at diagnosis or later | 179/250 (71.6 %) | NA | 86/128 (67.2 %) | NA | 93/122 (76.2 %) | NA |
Current smokers at inclusion | 155 (53.8 %) | 486 (42.9 %) | 64 (46.0 %) | 197 (35.4 %) | 91 (60.3 %) | 289 (47.8 %) |
Ever smokers at inclusion | 181/260 (69.6 %) | 625/1037 (60.3 %) | 25/139 (61.2 %) | 295/553 (53.3 %) | 96/121 (79.3 %) | 330/484 (68.2 %) |
Blue-collar worker | 146 (50.3 %) | 496 (42.8 %) | 67 (48.2 %) | 230 (41.4 %) | 79 (52.3 %) | 266 (44.0 %) |
White-collar worker | 107 (36.9 %) | 511 (44.1 %) | 55 (39.6 %) | 253 (45.5 %) | 52 (34.4 %) | 258 (42.7 %) |
Early menopause (at age <46 years)* | NA | NA | 24 % | 17 % | NA | NA |
Total cholesterol in mmol/l, mean (SD) | 5.84 (1.11) | 5.67 (1.04) | 6.04 (1.16) | 5.71 (1.10) | 5.66 (1.02) | 5.64 (0.98) |
Triglycerides in mmol/l, | 1.13 (0.78–1.57) | 1.12 (0.83–1.55) | 0.98 (0.76–1.48) | 0.95 (0.72–1.31) | 1.25 (0.90–1.70) | 1.30 (0.98–1.77) |
Median (IQR) | ||||||
BMI in kg/m2, | 24.3 (3.5) | 24.7 (3.7) | 24.3 (4.1) | 24.3 (4.3) | 24.3 (2.7) | 25.0 (3.3) |
mean (SD) | ||||||
ESR in mm, median (IQR) | 6 (4–11) | 6 (4–10) | 9 (5–14) | 8 (5–12) | 5 (3–8) | 4 (3–7) |
Full self-reported health | 208/290 (72 %) | 795/1155 (69 %) | 99/139 (71 %) | 364/551 (66 %) | 109/151(72 %) | 431/604 (71 %) |
Self-reported cancer | 8/260 (3 %) | 28/1037 (3 %) | 6/139 (4 %) | 27/553 (5 %) | 2/121 (2 %) | 1/484 (0.2 %) |
Self-reported diabetes | 12/259 (5 %) | 35/1036 (3 %) | 9/138 (6 %) | 25/562 (4 %) | 3/121 (2 %) | 10/484 (2 %) |
Self-reported cardiovascular disease | 8/260 (3 %) | 27/1037 (3 %) | 6/139 (4 %) | 20/553 (4 %) | 2/121 (2 %) | 7/484 (1 %) |