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Table 1 Incident cases of rheumatoid arthritis and controls: characteristics and lipid levels, stratified by sex

From: High serum cholesterol predicts rheumatoid arthritis in women, but not in men: a prospective study

  All   Women   Men  
  Cases Controls Cases Controls Cases Controls
Number 290 1160 139 556 151 604
Age at inclusion 47.1 (7.1) 47.1 (7.1) 49.3 (7.4) 49.3 (7.4) 45.5 (6.2) 45.5 (6.2)
Years; mean (SD)
Time from inclusion to RA diagnosis 12 (8–18) NA 11 (7–16) NA 13 (9–19) NA
Years; median (IQR)
Age at diagnosis 59.9 (8.8; 30–81) NA 60.8 (8.4; 30–76) NA 59.1 (9.0; 40–81) NA
Years; mean (SD; range)
RF-positive at diagnosis or later 179/250 (71.6 %) NA 86/128 (67.2 %) NA 93/122 (76.2 %) NA
Current smokers at inclusion 155 (53.8 %) 486 (42.9 %) 64 (46.0 %) 197 (35.4 %) 91 (60.3 %) 289 (47.8 %)
Ever smokers at inclusion 181/260 (69.6 %) 625/1037 (60.3 %) 25/139 (61.2 %) 295/553 (53.3 %) 96/121 (79.3 %) 330/484 (68.2 %)
Blue-collar worker 146 (50.3 %) 496 (42.8 %) 67 (48.2 %) 230 (41.4 %) 79 (52.3 %) 266 (44.0 %)
White-collar worker 107 (36.9 %) 511 (44.1 %) 55 (39.6 %) 253 (45.5 %) 52 (34.4 %) 258 (42.7 %)
Early menopause (at age <46 years)* NA NA 24 % 17 % NA NA
Total cholesterol in mmol/l, mean (SD) 5.84 (1.11) 5.67 (1.04) 6.04 (1.16) 5.71 (1.10) 5.66 (1.02) 5.64 (0.98)
Triglycerides in mmol/l, 1.13 (0.78–1.57) 1.12 (0.83–1.55) 0.98 (0.76–1.48) 0.95 (0.72–1.31) 1.25 (0.90–1.70) 1.30 (0.98–1.77)
Median (IQR)
BMI in kg/m2, 24.3 (3.5) 24.7 (3.7) 24.3 (4.1) 24.3 (4.3) 24.3 (2.7) 25.0 (3.3)
mean (SD)
ESR in mm, median (IQR) 6 (4–11) 6 (4–10) 9 (5–14) 8 (5–12) 5 (3–8) 4 (3–7)
Full self-reported health 208/290 (72 %) 795/1155 (69 %) 99/139 (71 %) 364/551 (66 %) 109/151(72 %) 431/604 (71 %)
Self-reported cancer 8/260 (3 %) 28/1037 (3 %) 6/139 (4 %) 27/553 (5 %) 2/121 (2 %) 1/484 (0.2 %)
Self-reported diabetes 12/259 (5 %) 35/1036 (3 %) 9/138 (6 %) 25/562 (4 %) 3/121 (2 %) 10/484 (2 %)
Self-reported cardiovascular disease 8/260 (3 %) 27/1037 (3 %) 6/139 (4 %) 20/553 (4 %) 2/121 (2 %) 7/484 (1 %)
  1. SD standard deviation, RA rheumatoid arthritis, IQR interquartile range, NA not applicable
  2. *Data available from 84 cases and 334 controls