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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: Twenty-eight-week results from the REALISTIC phase IIIb randomized trial: efficacy, safety and predictability of response to certolizumab pegol in a diverse rheumatoid arthritis population

Fig. 2

Treatment response to week 28. a ACR20 response rates up to week 28. b ACR50 and ACR70 response rates up to week 28 c DAS28(CRP) change from baseline up to week 28. d HAQ-DI change from baseline up to week 28 (OL set, imputed data). Footnote: ACR response rates were calculated using NRI if withdrawal was due to an AE or lack or loss of efficacy, and LOCF in case of any other reason. Least squares means (change from baseline) in DAS28(CRP) and HAQ-DI were analyzed using MMRM. AE adverse event, CRP C-reactive protein, CZP certolizumab pegol, DAS28 Disease Activity Score in 28 joints, HAQ-DI Health Assessment Questionnaire-Disability Index, LOCF last observation carried forward, MMRM mixed-effects model for repeated measures, NRI nonresponder imputation, OL open-label

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Arthritis Research & Therapy

ISSN: 1478-6362

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