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Table 5 Adiposity, metabolic and inflammation markers in RA patients grouped by sLep and sLepR quartiles

From: Serum leptin and serum leptin/serum leptin receptor ratio imbalance in obese rheumatoid arthritis patients positive for anti-cyclic citrullinated peptide antibodies

sLep ng/Ml

Quartile 1

Quartile 2

Quartile 3

Quartile 4

<36.27

36.27–72.75

72.76 –177.48

>177.48

n = 14

n = 16

n = 17

n = 17

Body fat ratio, kg/m2

5.92 ± 2.42

8.34 ± 2.90

11.16 ± 2.58

13.82 ± 3.43

ESR, mm/h

18.37 ± 10.53

19.37 ± 11.76

20.17 ± 13.14

27.17 ± 13.65

HOMA-IR

2.23 ± 2.11

3.52 ± 3.98

3.4 ± 2.55

8.25 ± 13.32

sLepR, ng/Ml

69.30 ± 17.62

48.24 ± 7.50

47.21 ± 11.48

36.48 ± 12.49

sLepR ng/Ml

Quartile 4

Quartile 3

Quartile 2

Quartile 1

>59.35

48.74–59.34

38.83–48.73

<38.83

n = 11

n = 14

n = 11

n = 15

Body fat ratio, kg/m2

6.59 ± 2.63

8.77 ± 2.56

9.30 ± 4.49

11.59 ± 4.73

ESR, mm/h

15.91 ± 9.26

18.14 ± 10.52

19.50 ± 9.90

27.94 ± 12.64

DAS-28 (ESR)

3.08 ± 1.46

3.09 ± 1.25

3.74 ± 1.05

4.02 ± 1.45

DAS-28 (CRP)

2.86 ± 1.37

2.82 ± 1.19

3.39 ± 1.06

3.64 ± 1.43

  1. FMI fat mass index, ESR erythrocyte sedimentation rate, HOMA-IR homeostatic model assessment insulin resistance, sLepR soluble leptin receptor, DAS-28 disease activity score in 28 joints, CRP C-reactive protein