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Table 5 Adiposity, metabolic and inflammation markers in RA patients grouped by sLep and sLepR quartiles

From: Serum leptin and serum leptin/serum leptin receptor ratio imbalance in obese rheumatoid arthritis patients positive for anti-cyclic citrullinated peptide antibodies

sLep ng/Ml Quartile 1 Quartile 2 Quartile 3 Quartile 4
<36.27 36.27–72.75 72.76 –177.48 >177.48
n = 14 n = 16 n = 17 n = 17
Body fat ratio, kg/m2 5.92 ± 2.42 8.34 ± 2.90 11.16 ± 2.58 13.82 ± 3.43
ESR, mm/h 18.37 ± 10.53 19.37 ± 11.76 20.17 ± 13.14 27.17 ± 13.65
HOMA-IR 2.23 ± 2.11 3.52 ± 3.98 3.4 ± 2.55 8.25 ± 13.32
sLepR, ng/Ml 69.30 ± 17.62 48.24 ± 7.50 47.21 ± 11.48 36.48 ± 12.49
sLepR ng/Ml Quartile 4 Quartile 3 Quartile 2 Quartile 1
>59.35 48.74–59.34 38.83–48.73 <38.83
n = 11 n = 14 n = 11 n = 15
Body fat ratio, kg/m2 6.59 ± 2.63 8.77 ± 2.56 9.30 ± 4.49 11.59 ± 4.73
ESR, mm/h 15.91 ± 9.26 18.14 ± 10.52 19.50 ± 9.90 27.94 ± 12.64
DAS-28 (ESR) 3.08 ± 1.46 3.09 ± 1.25 3.74 ± 1.05 4.02 ± 1.45
DAS-28 (CRP) 2.86 ± 1.37 2.82 ± 1.19 3.39 ± 1.06 3.64 ± 1.43
  1. FMI fat mass index, ESR erythrocyte sedimentation rate, HOMA-IR homeostatic model assessment insulin resistance, sLepR soluble leptin receptor, DAS-28 disease activity score in 28 joints, CRP C-reactive protein