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Table 3 Prevalences, tetrachorics, case-wise concordance rates, heritability, biometric models and chi-squared test statistics

From: Probability and heritability estimates on primary osteoarthritis of the hip leading to total hip arthroplasty: a nationwide population based follow-up study in Danish twins

Model

MZ prevalence

DZ prevalence

MZr

DZr

MZcw

DZcw

Heritability

Variance component estimates

Chisquare test statistics

AIC

A

D

C

E

LL

Chisquare

df

p

Men

                

 Saturated

0.06

0.06

0.80 (0.57–0.91)

0.41 (0.09–0.65)

0.51 (0.33–0.70)

0.21 (0.10–0.40)

0.78 (0.07–0.99)

–

–

–

–

–621.44

 

6

 

1254.88

 ACE

0.06

0.06

0.80 (0.57–0.91)

0.41 (0.09–0.65)

0.51 (0.33–0.70)

0.21 (0.10–0.40)

0.78 (0.07–0.99)

0.78 (0.07–0.99)

–

0.02 (0.00–1.0)

0.20 (0.08–0.41)

–621.44

 

6

 

1254.88

 ADE

0.06

0.06

0.80 (0.58–0.91)

0.40 (0.32–0.47)

0.51 (0.34–0.69)

0.21 (0.16–0.26)

0.80 (0.60–0.91)

0.80 (0.60–0.91)

0.00 (0.00–1.00)

–

0.20 (0.09–0.40)

    

1255.30

 AE

0.06

0.06

0.80 (0.58–0.91)

0.40 (0.32–0.47)

0.51 (0.34–0.69)

0.21 (0.16–0.26)

0.80 (0.60–0.91)

0.80 (0.60–0.91)

–

–

0.20 (0.09–0.40)

–621.65

0.42

2

0.81

 

 CE

0.07

0.07

0.63 (0.44–0.76)

0.63 (0.44–0.76)

0.37 (0.26–0.50)

0.37 (0.26–0.50)

–

–

–

0.63 (0.46–0.77)

0.37 (0.23–0.54)

–2921.4

4600

2

<0.0001

 

Women

    

 Saturated

0.06

0.06

0.72 (047–0.87)

0.46 (0.15–0.69)

0.42 (0.25–0.61)

0.23 (0.11–0.43)

0.52 (0.07–0.94)

–

–

–

–

–621.44

 

6

 

1254.88

 ACE

0.06

0.06

0.72 (0.47–0.87)

0.46 (0.15–0.69)

0.42 (0.25–0.61)

0.23 (0.11–0.43)

0.52 (0.07–0.94)

0.52 (0.07–0.94)

–

0.20 (0.006–0.91

0.28 (0.13–0.50)

–621.44

 

6

 

1254.88

 ADE

0.06

0.06

0.74 (0.52–0.87)

0.37 (0.28–0.45)

0.44 (0.28–0.61)

0.18 (0.14–0.24)

0.74 (0.54–0.87)

0.74 (0.54–0.87)

0.00 (0.00–1.00)

 

0.26 (0.13–0.46)

    

1255.30

 AE

0.06

0.06

0.74 (0.52–0.87)

0.37 (0.28–0.45)

0.44 (0.28–0.61)

0.18 (0.14–0.24)

0.74 (0.54–0.87)

0.74 (0.54–0.87)

–

–

0.26 (0.13–0.46)

–621.65

0.42

6

0.81

 

 CE

0.07

0.07

0.66 (0.48–0.79)

0.66 (0.48–0.79)

0.37 (0.26–0.50)

0.37 (0.26–0.50)

–

–

–

0.66 (0.50–0.79)

0.34 (0.21–0.50)

–2921.4

4600

2

<0.0001

 

Sex-adjusted

    

 Saturated

0.06

0.06

0.68 (0.55–078)

0.45 (0.23–0.62)

0.39 (0.30–0.50)

0.23 (0.14–0.36)

0.47 (0.12–0.85)

–

–

–

–

–806.7

 

2

 

1621.34

 ACE

0.06

0.06

0.68 (0.55–0.78)

0.45 (0.23–0.62)

0.39 (0.30–0.50)

0.23 (0.14–0.36)

0.47 (0.12–0.85)

0.47 (0.12–0.85)

–

0.22 (0.02–0.76)

0.31 (0.21–0.44)

–806.7

–

4

 

1621.34

 ADE

0.06

0.06

0.70 (0.57–0.80)

0.35 (0.29–0.40)

0.41 (0.31–0.51)

0.18 (0.15–0.21)

0.70 (0.58–0.79)

0.70 (0.58–0.80)

0.00 (0.00–0.00)

–

0.30 (0.21–0.42)

    

1622.31

 AE

0.06

0.06

0.70 (0.58–0.79)

0.35 (0.29–0.40)

0.41 (0.31–0.51)

0.18 (0.15–0.21)

0.70 (0.58–0.79)

0.70 (0.58–0.79)

–

–

0.30 (0.21–0.42)

–807.2

0.97

1

0.325

 

 CE

0.07

0.07

0.62 (0.51–0.71)

0.62 (0.51–0.71)

0.37 (0.29–0.45)

0.37 (0.29–0.45)

–

–

–

0.62 (0.52–0.72)

0.38 (0.28–0.48)

–2913.8

4214

1

<0.0001

 
  1. A Additive genetic, AIC Akaiki’s information criterion, C Common environment, D Dominant genetic, DZcw Dizygotic case-wise concordance rate, DZr Dizygotic correlation, E Unique environment, MZcw Monozygotic case-wise concordance rate, MZr Monozygotic correlation, Saturated Saturated model not including censoring
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Arthritis Research & Therapy

ISSN: 1478-6362

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