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Table 1 Baseline characteristics

From: Serum tenascin-C discriminates patients with active SLE from inactive patients and healthy controls and predicts the need to escalate immunosuppressive therapy: a cohort study

 

SLE (n = 59)

Healthy controls (n = 65)

Female sex

55 (93 %)

45 (69 %)

Age, yr

44 ± 16

48 (14)

Caucasian

59 (100 %)

65 (100 %)

Disease duration, yr

7 ± 7

 

SLICC/ACR Damage Index

0.8 ± 1.4

 

SLEDAI-2 K

3.7 ± 3.5

 

 cSLEDAI-2 K (only clinical SLEDAI-2 K items)

2.2 ± 3.0

 

 SLEDAI-2 K ≥4

30 (53 %)

 

 SLEDAI-2 K ≥6

19 (33 %)

 

 Any SLEDAI-2 K clinical features

26 (45 %)

 

 Neuropsychiatric featuresa

2 (3 %)

 

 Vasculitisa

0 (0 %)

 

 Arthritisa

10 (17 %)

 

 Myositisa

0 (0 %)

 

 Renal featuresa

8 (14 %)

 

 Rasha

9 (15 %)

 

 Alopeciaa

5 (9 %)

 

 Mucosal ulcersa

0 (0 %)

 

 Serositisa

1 (2 %)

 

 Haematological featuresa

3 (5 %)

 

 Fevera

0 (0 %)

 

 Increased DNA bindinga

22 (38 %)

 

 Low complementa

28 (48 %)

 

Anti-nucleosome antibody–positive

25 (46 %)

 

Oral glucocorticoids

35 (59 %)

 

Immunosuppressants

15 (25 %)

 
  1. ANA anti-nuclear antibodies, SLEDAI-2 K Systemic Lupus Erythematosus Disease Activity Index 2000, anti-dsDNA anti–double-stranded DNA, SLICC/ACR Systemic Lupus International Collaborating Clinics/American College of Rheumatology, SLE systemic lupus erythematosus
  2. Data are presented as number and percentage or mean and standard deviation
  3. aAccording to SLEDAI-2 K definitions; renal, haematological, serositis and neuropsychiatric SLEDAI-2 K features were merged into one item (see Definitions section in text)