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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Effect of abatacept on the immunogenicity of 23-valent pneumococcal polysaccharide vaccination (PPSV23) in rheumatoid arthritis patients

Fig. 3

a Comparison of post-vaccination GMC responses in patients receiving DMARDs (control), MTX and ABT/MTX. Percentages of patients with an increase in 6B and 23F serotype-specific IgG concentration greater than two-fold are shown. There were significant differences in the 6B and 6B/23F serotype-specific IgG response rates between control and ABT/MTX groups (6B; p = 0.012, 6B + 23F; p = 0.021). Data were compared using the Pearson chi-square test. b Comparison of post-vaccination OI responses in patients receiving DMARDs (control), MTX and ABT/MTX. Percentage of patients with an increase in OIs for serotypes 6B and 23F greater than ten-fold are shown. There was no significant difference in the response rates among control, MTX and ABT/MTX groups. Data were compared using the Pearson chi-square test. GMC geometric mean concentration, DMARDS disease modifying anti-rheumatic drugs, MTX methotrexate, ABT abatacept, OIs opsonization index

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Arthritis Research & Therapy

ISSN: 1478-6362

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