Variable | Low prescriber group (OR, 95 % CI) | High prescriber group (OR, 95 % CI) | p value** |
---|---|---|---|
Demographics | Â | Â | Â |
Age (decades) | 1.15, 1.11–1.20* | 1.26, 1.23–1.29* | <0.001 |
Gender (female) | 0.98, 0.87–1.10 | 0.89, 0.82–0.97* | 0.211 |
Current smoker (versus never) | 1.09, 1.02–1.17* | 1.07, 1.02–1.13* | 0.744 |
GC-associated comorbidities | Â | Â | Â |
Osteoporosis | 1.49, 1.14–1.95* | 1.84, 1.50–2.25* | 0.225 |
Avascular necrosis | 2.28, 0.32–16.22 | 1.84, 0.36–9.51 | 0.870 |
Myopathy | 2.29, 0.57–9.15 | 1.23, 0.45–3.38 | 0.479 |
Diabetes mellitus | 0.88, 0.72–1.08 | 1.02, 0.88–1.18 | 0.257 |
Cardiovascular disease | 1.38, 1.04–1.84* | 1.62, 1.31–2.00* | 0.373 |
Hypertension | 1.08, 0.95–1.24 | 1.29, 1.17–1.41* | 0.039 |
Hyperlipidaemia | 1.10, 0.92–1.31 | 1.07, 0.94–1.22 | 0.829 |
Peptic ulcer disease | 1.36, 1.06–1.74* | 1.33, 1.09–1.63* | 0.910 |
Pancreatitis | 1.00, 0.49–2.05 | 1.44, 0.81–2.54 | 0.442 |
Depression | 1.09, 0.96–1.23 | 1.09, 0.99–1.20 | 0.994 |
Insomnia | 1.27, 1.08–1.50* | 1.36, 1.20–1.54* | 0.548 |
Psychosis | 1.14, 0.60–2.17 | 1.29, 0.78–2.14 | 0.767 |
Prior use | Â | Â | Â |
GC prescription prior to follow up | 6.52, 5.51–7.71* | 11.76, 10.24–13.51* | <0.001 |