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Fig. 6 | Arthritis Research & Therapy

Fig. 6

From: In vivo optical imaging of early osteoarthritis using an antibody specific to damaged arthritic cartilage

Fig. 6

SNRs achieved by 1-11E and C7 full-length antibody and scFv for destabilised medial meniscus (DMM) surgery. SNR is expressed as the ratio of signal from the operated knee joint to the corresponding contralateral joint. Cy5.5-1-11E-scFv injected intra-arterially (i.a.) 4 weeks (a) and 8 weeks (b) post-DMM compared to sham operation (p < 0.001 for both 4 and 8 weeks). For mAb, SNR for Cy5.5-1-11E-mAb is compared to Cy5.5-C7-mAb injected intravenously (i.v.) 4 weeks (c) and 8 weeks (d) post-DMM. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001

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Arthritis Research & Therapy

ISSN: 1478-6362

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