|  | Grade |
---|---|---|
I | Structure | Â |
 | a. Normal | 0 |
 | b. Surface irregularity | 1 |
 | c. Pannus and surface irregularity | 2 |
 | d. Clefts to transitional zone | 3 |
 | e. Clefts to radial zone | 4 |
 | f. Clefts to calcified zone | 5 |
 | g. Complete disorganization | 6 |
II | Cells | Â |
 | a. Normal | 0 |
 | b. Diffuse hypercellularity | 1 |
 | c. Cloning | 2 |
 | d. Hypocellularity | 3 |
III | Safranin–Orange staining |  |
 | a. Normal | 0 |
 | b. Slight reduction | 1 |
 | c. Moderate reduction | 2 |
 | d. Severe reduction | 3 |
 | e. No dye note | 4 |
IV | Tidemark integrity | Â |
 | a. Intact | 0 |
 | b. Crossed by blood vessels | 1 |