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Fig. 2 | Arthritis Research & Therapy

Fig. 2

From: High-mobility group box 1 potentiates antineutrophil cytoplasmic antibody-inducing neutrophil extracellular traps formation

Fig. 2

HMGB1 plus ANCA-positive-IgG induces NETs formation in vitro. Human neutrophils were activated in vitro and then processed for immunofluorescence. a Representative images show neutrophil DNA (blue). b Representative images show immunostained with anti-human myeloperoxidase antibodies against myeloperoxidase (red). c Representative images show immunostained with anti-Cit-histone H3 antibodies against the histone H3 complex (green). d Representative images show merged neutrophil DNA (blue), histone H3 (green) and myeloperoxidase (red) staining. ANCA antineutrophil cytoplasmic antibody, HMGB1 high-mobility group box 1, IgG immunoglobulin G, NETs neutrophil extracellular traps

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Arthritis Research & Therapy

ISSN: 1478-6362

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