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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: High-mobility group box 1 potentiates antineutrophil cytoplasmic antibody-inducing neutrophil extracellular traps formation

Fig. 3

Dose–response curve of HMGB1 and ANCA-positive IgG on NETs information. a Dose–response curve for HMGB1 on potentiating ANCA-inducing NETs formation. b Dose–response curve for MPO-ANCA-positive IgG-inducing NETs formation. c Dose–response curve for PR3-ANCA-positive IgG-inducing NETs formation. Bars represent mean of repeated measurements on neutrophils of 4 independent experiments. ANCA antineutrophil cytoplasmic antibody, HMGB1 high-mobility group box 1, IgG immunoglobulin G, MPO myeloperoxidase, NETs neutrophil extracellular traps, PR3 proteinase 3

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