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Table 1 Patient characteristics

From: Reduced pro-inflammatory profile of γδT cells in pregnant patients with rheumatoid arthritis

 

Healthy control

Rheumatoid arthritis

Ankylosing spondylitis

Total number

 Total

35

55

31

 Non-pregnant

12

27

10

 Pregnant

23

28

21

Age in years; median (range)

 Non-pregnant

30.5 (24–48)

32.5 (17–51)

35 (30–47)

 Pregnant

33 (23–41)

32 (28–39)

32.5 (27–39)

Rheumatoid factor positive

 Non-pregnant

 

19 (59.4)

 

 Pregnant

 

13 (46.4)

 

ACPA positive

 Non-pregnant

 

17 (53.1)

 

 Pregnant

 

12 (42.9)

 

HLA-B27 positive

 Non-pregnant

  

7 (70)

 Pregnant

  

14 (66.7)

Medication

NSAID

 Non-pregnant

25 (75.8)

7 (70)

 3rd trimester

4 (14.3)

5 (23.8)

 Postpartum*

7 (25)

9 (42.9)

Prednisone**

 Non-pregnant

12 (36.4)

1 (10)

 3rd trimester

13 (46.4)

3 (14.3)

 Postpartum*

9 (32.1)

2 (9.5)

Sulfasalazine

 Non-pregnant

8 (24.2)

1 (10)

 3rd trimester

5 (17.9)

 Postpartum*

7 (25)

1 (4.8)

Antimalarials

 Non-pregnant

1 (3)

 3rd trimester

2 (7.1)

 Postpartum*

5 (17.9)

Methotrexate

 Non-pregnant

7 (21.2)

 3rd trimester

 Postpartum*

Leflunomide

 Non-pregnant

1 (3)

 3rd trimester

 Postpartum*

TNF inhibitors

 Non-pregnant

5 (15.2)

3 (30)

 3rd trimester

 Postpartum*

 

2 (9.5)

  1. All values are shown as n (%) except where indicated otherwise. *Postpartum: 6–8 weeks after birth; ** < 15 mg/day. ACPA anti citrullinated peptide antibodies, NSAID Non-steroidal anti-inflammatory drug (until gestation week 32), TNF Tumor necrosis factor