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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Bone marrow lesions detected by specific combination of MRI sequences are associated with severity of osteochondral degeneration

Fig. 3

Comparison of cartilage volume (a), Osteoarthritis Research Society International; (OARSI) grades (b), cartilage tidemark progression (arrows identify tidemarks) (c), penetration of vascular cones (circled) (d). Histopathology of bone marrow; bone marrow edema (e), fibrosis (f), necrosis (g), thick-walled arterioles (h) and fibrovascular cystic formation (i). Represented histologically and graphically for specimens with no bone marrow lesions evident (No BML), bone marrow lesions evident only in fast spin-echo proton density-weighted (PDFS) sequences (BML 1), and bone marrow lesions evident in both PDFS and T1-weighted sequences (BML 2): *p = 0.05, **p = 0.005, ***p = 0.0005

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