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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Colony-stimulating factor (CSF) 1 receptor blockade reduces inflammation in human and murine models of rheumatoid arthritis

Fig. 3

Gene expression in differentiated macrophages. a mRNA expression profiles of 336 genes involved in angiogenesis, extracellular matrix remodeling, and osteoclast formation in granulocyte-macrophage colony-stimulating factor (GM-CSF)-, colony-stimulating factor-1 (CSF-1)- or IL-34-differentiated macrophages (Mφ) derived from monocytes of buffy coats (n = 3). Data are presented in an unsupervised clustergram. b Analyses of mRNA expression levels of selected genes analyzed in a. Data are shown as relative quantity (RQ) in relation to GM-CSF Mφ, as described in “Methods

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