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Table 1 Characteristics of patients with systemic lupus erythematosus

From: CD163+ M2c-like macrophages predominate in renal biopsies from patients with lupus nephritis

  ISN/RPS class  
  II III IV V Sum/mean
Number of patients 8 13 26 21 68
Age, years 32.6 ± 18.7 32.3 ± 11.9 31.4 ± 14.6 36.7 ± 16.3 33.3 ± 15.0
Male 1 1 4 5 11
Female 7 12 22 16 57
Ratio male/female 0.14 0.08 0.17 0.31 0.19
Hypertensive patients, % 25 31 27 29 28
Diabetic patients, % 13 0 0 10 6
GSI 0.9 ± 0.7* 1.2 ± 0.7* 2.1 ± 0.5 1.1 ± 0.9* 1.3 ± 0.7
TSI 0.8 ± 0.6 1.4 ± 0.7 1.3 ± 0.4 1.0 ± 0.7 1.1 ± 0.6
Crescents, yes/no 0/8* 9/4 20/6 0/21* 29/38
Proteinuria, g/day 2.3 ± 3.2 3.0 ± 3.3 3.3 ± 2.4 4.8 ± 1.8 3.5 ± 2.7
Serum creatinine, mg/dl 0.9 ± 0.5 0.9 ± 0.4 1.0 ± 0.5 1.2 ± 1.0 1.0 ± 0.6
GFR, ml/min 139.5 ± 79.9 74.3 ± 32.4 75.1 ± 26.8 97.9 ± 42.1 95.8 ± 53.4
Austin activity score (0–24) 2.5 ± 0.9* 5.8 ± 1.5* 9.5 ± 4.2 1.7 ± 1.3* 5.9 ± 4.5
  1. The mean values are presented as mean ± SD
  2. *p < 0.01 vs. ISN/RPS class IV; p < 0.05 vs. International Society of Nephrology/Renal Pathology Society (ISN/RPS) class III. GFR glomerular filtration rate, GSI glomerulosclerosis score, TSI tubular injury score