From: CD163+ M2c-like macrophages predominate in renal biopsies from patients with lupus nephritis
ISN/RPS class | |||||
---|---|---|---|---|---|
II | III | IV | V | Sum/mean | |
Number of patients | 8 | 13 | 26 | 21 | 68 |
Age, years | 32.6 ± 18.7 | 32.3 ± 11.9 | 31.4 ± 14.6 | 36.7 ± 16.3 | 33.3 ± 15.0 |
Male | 1 | 1 | 4 | 5 | 11 |
Female | 7 | 12 | 22 | 16 | 57 |
Ratio male/female | 0.14 | 0.08 | 0.17 | 0.31 | 0.19 |
Hypertensive patients, % | 25 | 31 | 27 | 29 | 28 |
Diabetic patients, % | 13 | 0 | 0 | 10 | 6 |
GSI | 0.9 ± 0.7* | 1.2 ± 0.7* | 2.1 ± 0.5 | 1.1 ± 0.9* | 1.3 ± 0.7 |
TSI | 0.8 ± 0.6 | 1.4 ± 0.7 | 1.3 ± 0.4 | 1.0 ± 0.7 | 1.1 ± 0.6 |
Crescents, yes/no | 0/8* | 9/4 | 20/6 | 0/21* | 29/38 |
Proteinuria, g/day | 2.3 ± 3.2 | 3.0 ± 3.3 | 3.3 ± 2.4 | 4.8 ± 1.8 | 3.5 ± 2.7 |
Serum creatinine, mg/dl | 0.9 ± 0.5 | 0.9 ± 0.4 | 1.0 ± 0.5 | 1.2 ± 1.0 | 1.0 ± 0.6 |
GFR, ml/min | 139.5 ± 79.9 | 74.3 ± 32.4 | 75.1 ± 26.8 | 97.9 ± 42.1 | 95.8 ± 53.4 |
Austin activity score (0–24) | 2.5 ± 0.9* | 5.8 ± 1.5* | 9.5 ± 4.2 | 1.7 ± 1.3*† | 5.9 ± 4.5 |