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Table 1 Characteristics of patients with systemic lupus erythematosus

From: CD163+ M2c-like macrophages predominate in renal biopsies from patients with lupus nephritis

 

ISN/RPS class

 
 

II

III

IV

V

Sum/mean

Number of patients

8

13

26

21

68

Age, years

32.6 ± 18.7

32.3 ± 11.9

31.4 ± 14.6

36.7 ± 16.3

33.3 ± 15.0

Male

1

1

4

5

11

Female

7

12

22

16

57

Ratio male/female

0.14

0.08

0.17

0.31

0.19

Hypertensive patients, %

25

31

27

29

28

Diabetic patients, %

13

0

0

10

6

GSI

0.9 ± 0.7*

1.2 ± 0.7*

2.1 ± 0.5

1.1 ± 0.9*

1.3 ± 0.7

TSI

0.8 ± 0.6

1.4 ± 0.7

1.3 ± 0.4

1.0 ± 0.7

1.1 ± 0.6

Crescents, yes/no

0/8*

9/4

20/6

0/21*

29/38

Proteinuria, g/day

2.3 ± 3.2

3.0 ± 3.3

3.3 ± 2.4

4.8 ± 1.8

3.5 ± 2.7

Serum creatinine, mg/dl

0.9 ± 0.5

0.9 ± 0.4

1.0 ± 0.5

1.2 ± 1.0

1.0 ± 0.6

GFR, ml/min

139.5 ± 79.9

74.3 ± 32.4

75.1 ± 26.8

97.9 ± 42.1

95.8 ± 53.4

Austin activity score (0–24)

2.5 ± 0.9*

5.8 ± 1.5*

9.5 ± 4.2

1.7 ± 1.3*

5.9 ± 4.5

  1. The mean values are presented as mean ± SD
  2. *p < 0.01 vs. ISN/RPS class IV; p < 0.05 vs. International Society of Nephrology/Renal Pathology Society (ISN/RPS) class III. GFR glomerular filtration rate, GSI glomerulosclerosis score, TSI tubular injury score