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Table 1 Association between smoking and RA in subgroups of patients, divided based on the presence/absence of anti-CEP-1 and anti-carb-CEP-1 antibodies

From: Antibodies to carbamylated α-enolase epitopes in rheumatoid arthritis also bind citrullinated epitopes and are largely indistinct from anti-citrullinated protein antibodies

CEP-1/carb-CEP-1

Smoking

ORa (95 % CI)

Never

Ever

Controls

2114 (43.46)

2750 (56.54)

Reference 1.0

–/–

575 (37.00)

979 (63.00)

1.23b (1.09, 1.39)

+/–

159 (24.54)

489 (75.46)

2.21b (1.82, 2.68)

–/+

29 (38.67)

46 (61.33)

1.15 (0.71, 1.86)

+/+

107 (21.10)

400 (78.90)

2.60b (2.07, 3.25)

  1. CEP-1 citrullinated α-enolase peptide-1, carb-CEP-1 carbamylated CEP-1, CI confidence interval, RA rheumatoid arthritis. aOdds ratios (OR) were adjusted for age, gender and residential area. bStatistically significant ORs