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Table 2 Serum proteins positively correlated with ESSDAI score in patients with pSS in first cohort (n = 30)

From: Identification of definitive serum biomarkers associated with disease activity in primary Sjögren’s syndrome

Protein

Spearman’s ρ

P value

EPHB-2

0.65

<0.0001

CXCL13

0.60

0.0005

CD48

0.56

0.0014

β2MG

0.55

0.0018

BAFF

0.52

0.0029

TNF-R2

0.51

0.0039

LAG-3

0.49

0.0058

CD163

0.49

0.0062

PD-L2

0.47

0.0081

  1. Spearman’s rho correlation coefficient test was used to test correlation between 82 differentially expressed protein concentrations and the European League Against Rheumatism Sjögren’s Syndrome Disease Activity Index (ESSDAI) scores. EPHB-2, ephrin type-B receptor 2, CXCL13, C-X-C motif chemokine 13, β2MG β2-microglobulin, BAFF B-cell activating factor, TNF-R2 TNF receptor 2, LAG-3, lymphocyte activation gene-3, PD-L2 programmed cell death protein 1 ligand 2A P value <0.01 was considered significant
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Arthritis Research & Therapy

ISSN: 1478-6362

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