Fig. 3
Bone marrow and splenic activity in RA patients. Cross-sectional 18F-FDG PET/CT images representing 18F-FDG uptake (red) in the aorta, bone marrow (top and bottom) and spleen (bottom) in a RA patient without (a) or with anti-TNF treatment (b). Quantification of maximum standard uptake values (SUVmax) showed increased activity in both bone marrow (c) and spleen (d) of RA patients with continued anti-TNF treatment versus RA patients without anti-TNF treatment and controls. * = p < 0.05, ** = p < 0.01. DMARD disease-modifying antirheumatic drug, RA rheumatoid arthritis, SUV standardized uptake values, TNF tumor necrosis factor