Fig. 2
From: Knockout of endothelin type B receptor signaling attenuates bleomycin-induced skin sclerosis in mice
ETBKO mice resist BLM-induced skin sclerosis. a Representative images of dermis sections stained with Masson's trichrome at 40× magnification. b Changes in dermal thickness (epidermal–dermal distance) and c subcutaneous fat atrophy (dermal–subcutaneous fat distance) in BLM- or PBS-treated WT and ETBKO mice; values are shown as the mean fold change from PBS-treated WT (WT-PBS) mice. d Collagen 1 deposition area in dermis of each mice group. (* p < 0.05) (n = 5–10 mice per group). BLM bleomycin, ET B KO endothelin type B receptor knockout, PBS phosphate-buffered saline, WT wild-type