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Fig. 4 | Arthritis Research & Therapy

Fig. 4

From: Antiphospholipid antibodies detected by line immunoassay differentiate among patients with antiphospholipid syndrome, with infections and asymptomatic carriers

Fig. 4

Inhibition of anti-beta2 glycoprotein I (aß2GPI) human monoclonal antibodies (humoAb) MBB2 and HCAL and antiphospholipid (aPL) humoAb RR7F by cardiolipin (CL) micelles in the line immunoassay (LIA): aß2GPI and aPL humoAb were run in the LIA alone or together with 10 mg/L CL micelles. As the positive reaction control a mixture of human IgG and IgM was immobilized. 1, 0.1 mg/L aß2GPI MBB2; 2, 0.1 mg/L aß2GPI MBB2 + CL micelles; 3, 0.02 mg/L aß2GPI HCAL; 4, 0.02 mg/L aß2GPI HCAL + CL micelles; 5, 10.0 mg/L aPL RR7F; and 6, 10.0 mg/L aPL RR7F + CL micelles

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