Fig. 3

Baseline expression of miR-125b in peripheral blood mononuclear cells is higher in responders than in non-responders. Patients with early rheumatoid arthritis were categorized as non-responders if they had moderate to high disease activity assessed by the 28-joint count disease activity score (DAS28 ≥ 3.2) and as responders if they achieved low disease activity or remission (DAS28 < 3.2) after 3 months of treatment. Horizontal line represents the median. P values were estimated using the nonparametric unpaired Mann-Whitney U test to calculate differences in the expression of miR-125b between responders and non-responders