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Fig. 7 | Arthritis Research & Therapy

Fig. 7

From: Curcumin slows osteoarthritis progression and relieves osteoarthritis-associated pain symptoms in a post-traumatic osteoarthritis mouse model

Fig. 7

Topical application of curcumin nanoparticles reduces osteoarthritis-related pain symptoms. Tactile sensitivity (von Frey testing) (a), and distance traveled (b) and number of times reared (c) per 6 minutes in an open field, in mice with destabilization of the medial meniscus (DMM) treated with curcumin nanoparticles (Nano-C) at 8 weeks after DMM surgery, did not differ from naïve controls (#p > 0.05, one-way analysis of variance (ANOVA) with Tukey post-hoc test, n = 5/group), but had significant improvement compared to mice with DMM treated with vehicle (Veh) (*p < 0.05, one-way ANOVA with Tukey post-hoc test, n = 5/group)

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