Fig. 4

Immunofluorescence analysis of renal immunoglobulin G (IgG) and complement component 3 (C3) deposits. Deposits of renal C3 (a) and IgG (b) were quantified with confocal microscopy, and the results were expressed as mean fluorescence intensity (MFI). All treatments reduced glomerular deposits. c Representative photomicrographs of C3 deposits (×630 original magnification) for each group. d Representative photomicrographs of IgG deposits (×630 original magnification) for each group. Data are expressed as mean ± SEM. *p < 0.05 vs control. CP CP-690,550; CYP cyclophosphamide; MMF mycophenolate mofetil