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Table 4 ROC analysis of ability of Pro-C2 and C-Col10 to differentiate between healthy control, psoriatic arthritis, and axial spondyloarthritis groups

From: Chondrocyte activity is increased in psoriatic arthritis and axial spondyloarthritis

  AUC (95 % CI) Youden index Sensitivity Specificity
Pro-C2     
 Healthy vs. axSpA 0.85 (0.79–0.89) 0.58 87.9 70.6
 Healthy vs. PsA 0.81 (0.75–0.86) 0.51 92.7 58.8
 axSpA vs. PsA 0.54 (0.47–0.61) 0.13 17.43 95.2
C-Col10     
 Healthy vs. axSpA 0.58 (0.51–0.65) 0.18 67.0 51.4
 Healthy vs. PsA 0.61 (0.54–0.67) 0.21 69.7 51.4
 axSpA vs. PsA 0.52 (0.45–0.59) 0.11 94.5 16.8
  1. axSpA axial spondyloarthritis, PsA psoriatic arthritis