Table 4 ROC analysis of ability of Pro-C2 and C-Col10 to differentiate between healthy control, psoriatic arthritis, and axial spondyloarthritis groups
From: Chondrocyte activity is increased in psoriatic arthritis and axial spondyloarthritis
AUC (95 % CI) | Youden index | Sensitivity | Specificity | |
|---|---|---|---|---|
Pro-C2 | ||||
Healthy vs. axSpA | 0.85 (0.79–0.89) | 0.58 | 87.9 | 70.6 |
Healthy vs. PsA | 0.81 (0.75–0.86) | 0.51 | 92.7 | 58.8 |
axSpA vs. PsA | 0.54 (0.47–0.61) | 0.13 | 17.43 | 95.2 |
C-Col10 | ||||
Healthy vs. axSpA | 0.58 (0.51–0.65) | 0.18 | 67.0 | 51.4 |
Healthy vs. PsA | 0.61 (0.54–0.67) | 0.21 | 69.7 | 51.4 |
axSpA vs. PsA | 0.52 (0.45–0.59) | 0.11 | 94.5 | 16.8 |