Fig. 6
From: Collagen-induced arthritis and imiquimod-induced psoriasis develop independently of interleukin-33
Imiquimod (IMQ)-induced skin inflammation develops independent of IL-33. IL-33-/- (n = 6) or WT (n = 6) mice were treated daily with IMQ cream. Erythema, scales, and thickness of the back skin were scored daily on a scale from 0 to 4 (a-c). The cumulative score (erythema plus scales plus thickness) is depicted (d). Data are mean score ± SEM of six mice per group. Epidermal thickness was measured on histological slides of the skin at day 11 (e), and scores are individual scores for all mice (n = 6 in both groups). The results are representative of two experiments (n = 19). IL interleukin, WT wild-type