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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: Concurrent validity of different functional and neuroproteomic pain assessment methods in the rat osteoarthritis monosodium iodoacetate (MIA) model

Fig. 3

Static weight-bearing (SWB) evolution after induction of osteoarthritis (least squares mean ± standard error of the mean). On day 3, the monosodium iodoacetate (MIA) intra-articular injection in the right knee induced asymmetrical weight distribution in the rats injected with MIA (adjusted P value (adj-P) = 0.0024) and rats injected with MIA and punctual lidocaine (MIA-L) (adj-P = 0.0011) compared to rats injected with 0.9 % saline (sham). Subsequently, a statistically significant difference in right hind paw SWB was only observed between the sham and MIA-L groups at days 7 and 21. %BW percentage of body weight. a,bSignificant inter-group statistical differences

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