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Table 5 Neuropeptides inter-group comparisons in the monosodium iodoacetate osteoarthritis rat model

From: Concurrent validity of different functional and neuroproteomic pain assessment methods in the rat osteoarthritis monosodium iodoacetate (MIA) model

Inter-group comparisons SP CGRP
Three groups vs. naive rats 0.016* 0.016*
MIA vs. sham 0.029* 0.029*
MIA-L vs. sham 0.057* 0.029*
MIA-L vs. MIA 0.029* 0.200
  1. MIA monosodium iodoacetate, MIA-L rats injected with monosodium iodoacetate and treated with punctual lidocaine injection, SP substance P, CGRP calcitonin gene related-peptide. *Inter-group statistically significant difference (adjusted P value)