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Fig. 5 | Arthritis Research & Therapy

Fig. 5

From: Whole blood expression profiling from the TREAT trial: insights for the pathogenesis of polyarticular juvenile idiopathic arthritis

Fig. 5

Mechanistic network derived from differential gene expression analysis of upstream regulators of differentially expressed genes using IPA and comparing untreated JIA to healthy controls. Nodes in orange reflect predicted activation, while those in blue are predicted to be inhibited based on the patterns of differential gene expression. CD3–T-cell receptor (TCR) activation is predicted from the pattern of gene expression

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