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Fig. 3 | Arthritis Research & Therapy

Fig. 3

From: MRI-detected osteitis is not associated with the presence or level of ACPA alone, but with the combined presence of ACPA and RF

Fig. 3

Bone marrow edema (BME) scores in patients with rheumatoid arthritis (RA) and undifferentiated arthritis (UA) (n=397) with different combinations of anti-citrullinated protein antibodies (ACPA), rheumatoid factor (RF) and anti-carbamylated protein antibodies (anti-CarP). Horizontal lines representing median. Whiskers show the 10th–90th percentile. Dots represent outliers. ACPA+, RF+, anti-CarP+ patients vs. ACPA-, RF-, anti-CarP- patients, p < 0.001; ACPA+, RF+, anti-CarP- patients vs. ACPA-, RF-, anti-CarP- patients, p < 0.001. ACPA-, RF-, anti-CarP- patients, n = 217; ACPA-, RF+, antiCarP- patients, n = 43; ACPA+, RF-, anti-CarP- patients, n = 14; ACPA+, RF+, anti-CarP- patients, n = 42; ACPA-, RF-, anti-CarP+ patients, n = 6; ACPA-, RF+, anti-CarP+ patients, n = 1; ACPA+, RF-, anti-CarP+ patients, n = 3; ACPA+, RF+, anti- CarP+ patients, n = 61. Total score: sum of BME scores in metacarpophalangeal, wrist, and metatarsophalangeal joints. *Significant difference between subgroups (p < 0.05)

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