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Table 2 Baseline characteristics of patients with high titers of anti-PF4/heparin antibody

From: Reduced induction of anti-PF4/heparin antibody in RA patients after total knee arthroplasty

  Postoperative seroconversion (OD ≥ 0.4)
Positive Negative  
(n = 28) (n = 96) p value
Gender(male/female) 6/22 14/82 0.275
Age (years), mean ± SD 73.8 ± 6.6 73.3 ± 7.0 0.551
BMI (kg/m2), mean ± SD 27.3 ± 3.9 26.5 ± 4.2 0.532
History of venous thrombosis, n (%) 1 (3.6 %) 6 (6.3 %) 0.503
Comorbidities, n (%)
 Hypertension 18 (64.3 %) 65 (67.7 %) 0.735
 Ischemic heart disease 2 (7.1 %) 4 (4.2 %) 0.409
 Diabetes 9 (32.1 %) 18 (18.8 %) 0.131
 Cerebrovascular disease 3 (10.7 %) 7 (7.3 %) 0.401
Operation time (min), mean ± SD 91.1 ± 20.6 94.3 ± 23.7 0.682
RA/OA 3/25 23/73 0.130
Foot pump, n (%) 12 (42.9 %) 47 (49.0 %) 0.569
Use of steroid, n (%) 2 (7.1 %) 16 (16.7 %) 0.171
Use of MTX, n (%) 1(3.6 %) 9 (9.4 %) 0.292
  1. BMI body mass index, OA osteoarthritis, OD optical density, RA rheumatoid arthritis, MTX methotrexate, PF4 platelet factor 4