Fig. 5

Increased expression of adhesion molecule CD54 (ICAM-1), chemokine receptor CCR5 and NKG2C on CD56^dim natural killer (NK) cells in active (non-remission) granulomatosis with polyangiitis (GPA). Experimental setting, patients and analysis as described in Fig. 3, using multicolor panel III. a Left mean fluorescent intensity (MFI) of CD54 on CD56^dim NK cells; Kruskal-Wallis test, p = 0.0108; middle percentage of CCR5-positive CD56^dim NK cells (Kruskal-Wallis test, p = 0.0204); right percentage of CXCR3-positive CD56^dim NK cells (Kruskal-Wallis test not significant). b Left percentage of NKG2C on CD56^dim NK cells (Kruskal-Wallis test, p = 0.0227); right percentage of NKG2C on CD56^bright NK cells (Kruskall-Wallis test not significant). a, b Dunn's post hoc test was significant where indicated in the graphs. HC healthy controls