Table 2 Associations between anti-RgpB IgG (stratified for above the 75th percentile vs below) and the development of RA in pre-symptomatic individuals and RA patients
Pre-symptomatic individuals (n = 251) | RA patients (n = 192) | |||||||
|---|---|---|---|---|---|---|---|---|
Simple logistic regression | Multiple logistic regression | Simple logistic regression | Multiple logistic regression | |||||
Variable | OR (95 % CI) | OR (95 % CI) | OR (95 % CI) | OR (95 % CI) | ||||
Anti-RgpB | 2.31 (1.41–3.78) | 2.24 (1.35–3.71) | 2.55 (1.67–4.43) | 2.17 (1.28–3.68) | 1.20 (0.75–1.92) | 1.18 (0.73–1.92) | 1.30 (0.77–2.17) | 1.22 (0.74–2.00) |
Ever smoker | 1.88 (1.26–2.78) | 2.14 (1.41–3.26) | ||||||
HLA-DRB1 SE | 3.58 (2.36–5.42) | 3.14 (2.05–4.83) | ||||||
PTPN22 1858 T-variant | 2.17 (1.36–3.48) | 2.16 (1.33–3.53) | ||||||