Ultrasonographic assessment of bone erosions in the different subtypes of systemic lupus erythematosus arthritis: comparison with computed tomography

Table 4 Main characteristics and distribution of US and CT abnormalities in patients with different subtypes of SLE arthropathy

	Rhupus (n = 9)	JA (n = 10)	NDNE (n = 7)	Rhupus vs JA (p value)	Rhupus vs NDNE (p value)	JA vs NDNE (p value)
Age, years (mean ± SD)	41.0 ± 5.7	61.3 ± 14.3	43.1 ± 16.4	0.001	0.765	0.035
Disease duration, years (mean ± SD)	13.7 ± 6.6	21.7 ± 10.7	10.8 ± 4.1	0.035	0.298	0.003
Rheumatoid factor	7 (77.8 %)	2 (20.0 %)	2 (28.5 %)	-	-	-
Anti-CCP	6 (66.7 %)	0 (0)	1 (14.2 %)	-	-	-
US erosion number (median (25th to 75^th percentile))	3.0 (1.7–4.2)	0.5 (0–2.0)	0 (0–1.0)	0.019	0.004	0.569
US quadrants with erosion	27 (10.7 %)	12 (4.3 %)	4 (2.0 %)	-	-	-
ScUSSe total (median (25th to 75^th percentile))	4.0 (2.5–6.0)	1.0 (0–3.0)	0 (0–1.0)	0.021	0.003	0.535
Grade 1 (<2 mm)	16^a	10^a	4^a	-	-	-
Grade 2 (2–3 mm)	9^a	1^a	0^a	-	-	-
Grade 3 (>3 mm)	2^a	1^a	0^a	-	-	-
CT erosion number (mean ± SD)	14.0 ± 9.7	5.7 ± 5.1	4.7 ± 4.5	0.050	0.030	0.543
RAMRIS (mean ± SD)	21.6 ± 18.2	7.4 ± 7.0	5.1 ± 5.0	0.053	0.029	0.448
RAMRIS MCP (median (25th to 75^th percentile))	6.0 (4.5–10.2)	1.0 (0–2.0)	0 (0–1.5)	0.013	0.009	0.353
RAMRIS wrist (median (25th to 75^th percentile))	8.0 (10.2–16.2)	3.5 (0–11.0)	3.0 (0.5–6.7)	0.111	0.057	0.694
Grade 1 (1–10 %)	24^a	21^a	6^a	-	-	-
Grade 2 (11–20 %)	19^a	6^a	6^a	-	-	-
Grade 3 − 10 (21–100 %)	7^a	1^a	2^a	-	-	-

Numbers in bold indicate statistical significance for p <0.05. Boxes are empty where statistics was not applied
^aAbsolute numbers referring to joint quadrants. JA Jaccoud’s arthropathy, NDNE non-deforming non-erosive, Anti-CCP anti-cyclic citrullinated peptide, US ultrasound, ScUSSe scoring ultrasound structural erosion, CT computed tomography, RAMRIS rheumatoid arthritis magnetic resonance imaging score, MCP metacarpophalangeal joint

ISSN: 1478-6362