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Table 3 Associations between IPFP hypointense signals and baseline bone marrow lesions and increases in bone marrow lesions over 2.6 years

From: Hypointense signals in the infrapatellar fat pad assessed by magnetic resonance imaging are associated with knee symptoms and structure in older adults: a cohort study

  Multivariablea Multivariableb
OR (95 % CI) OR (95 % CI)
Baseline bone marrow lesions
 Any bone marrow lesions 1.64 (1.32, 2.03) 1.11 (0.87, 1.42)
 Medial tibiofemoral 1.77 (1.39, 2.25) 1.24 (0.95, 1.63)
 Lateral tibiofemoral 1.40 (1.08, 1.80) 1.03 (0.78, 1.36)
 Patellar 1.21 (0.93, 1.57) 0.83 (0.61, 1.13)
Increases in bone marrow lesions
 Any bone marrow lesions 1.91 (1.39, 2.62) 1.45 (1.02, 2.04)
 Medial tibiofemoral 2.11 (1.46, 3.07) 1.59 (1.06, 2.39)
 Lateral tibiofemoral 1.66 (1.17, 2.35) 1.36 (0.93, 1.97)
 Patellar 1.50 (1.04, 2.15) 1.34 (0.92, 1.95)
  1. Dependent variables: baseline bone marrow lesions or increases in bone marrow lesions (yes v no); independent variables: IPFP hypointense signals (per grade)
  2. IPFP infrapatellar fat pat
  3. aAdjusted for age, sex, BMI, and radiographic osteoarthritis
  4. bFurther adjustment for cartilage defects