Fig. 4
From: Screening for peptides targeted to IL-7Rα for molecular imaging of rheumatoid arthritis synovium
Signal enhancement (% difference in signal-to-noise ratio (ΔSNR%)) measured on sagittal (a) and coronal (b) magnetic resonance images of the paw in mice with collagen-induced arthritis (CIA) and healthy mice injected with ultra-small superparamagnetic particles of iron oxide (USPIO)-P258 or USPIO-poly(ethylene glycol) (USPIO-PEG): n = 4 per experimental group; p < 0.01 for CIA mice injected with USPIO-P258 as compared to all control groups, except for the coronal slices acquired at 26 minutes post contrast and compared to USPIO-PEG, for which p < 0.05. For transverse relaxation rates (R 2 ), R2(1) (c) and R2(2) (d) were measured on paws sampled from mice at the end of the imaging session