Table 3 Pharmacokinetic parameters of USPIO-P258 in comparison to USPIO-PEG, as determined in healthy NMRI mice
From: Screening for peptides targeted to IL-7Rα for molecular imaging of rheumatoid arthritis synovium
Pharmacokinetic parameters | USPIO-P258 | USPIO-PEG |
|---|---|---|
Te1/2 (minutes) | 118 | 284 |
VDss (L/kg) | 0.100 | 0.0475 |
Cltot (mL/min/kg) | 0.595 | 0.116 |