Fig. 3

C3b deposition in kidney biopsies from patients with scleroderma renal crisis (SRC). Shown are representative micrographs of kidney biopsy cores immunostained for C3b. a An example of a biopsy obtained from a patient with SRC, which was negative for C3b. b Example of a biopsy positive for C3b in glomeruli. c Example of a biopsy positive for C3b in tubules. d Positive control biopsy from patient diagnosed for immunoglobulin A nephropathy with distinct glomerular C3 positivity