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Table 3 Association between smoking and different RA subsets according to the presence/absence of anti-CarP antibodies, ACPA and RF

From: Prevalence, sensitivity and specificity of antibodies against carbamylated proteins in a monocentric cohort of patients with rheumatoid arthritis and other autoimmune rheumatic diseases

Smoking

Disease subset

Patients, n

Never smoked, n (%)

Ever smoked, n (%)

95% CI

P value

Anti-CarP (−)/ACPA (−)/RF (−)

62

31 (50%)

31 (50%)

−2.2–2.2

ns

Anti-CarP (+)/ACPA (+)/RF (+)

82

32 (39%)

50 (61%)

19.7–24.7

0.0001

Anti-CarP (−)/ACPA (+)/RF (+)

89

40 (45%)

49 (55%)

7.7–12.2

0.0001

Anti-CarP (+)/ACPA (−)/RF (−)

26

14 (53.8%)

12 (46.2%)

−4.2–0.2

ns

Anti-CarP (−)/ACPA (+)/RF (−)

15

6 (40%)

9 (60%)

0.7–5.2

0.02

Anti-CarP (−)/ACPA (−)/RF (+)

26

14 (53.8%)

12 (46.2%)

−4.2–0.2

ns

Anti-CarP (+)/ACPA (+)/RF (−)

4

2 (50%)

2 (50%)

−2.2–2.2

ns

Anti-CarP (+)/ACPA (−)/RF (+)

5

3 (60%)

2 (40%)

−3.2–1.2

ns

  1. RA rheumatoid arthritis, Anti-CarP antibodies against carbamylated proteins, ACPA anti-citrullinated protein antibodies, RF rheumatoid factor, ns not significant