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Table 4 Diagnostic performance of anti-CarP antibodies, ACPA and RF

From: Prevalence, sensitivity and specificity of antibodies against carbamylated proteins in a monocentric cohort of patients with rheumatoid arthritis and other autoimmune rheumatic diseases

 

Sensitivity (95% CI)

Specificity (95% CI)

LR

PPV

NPV

Anti-CarP

46.8 (41.50–52.54)

91.95 (82.25–94.77)

4.581

88%

60%

ACPA

61.8 (56.14–67.25)

89.93 (85.94–93.10)

6.14

85%

62%

RF

64.4 (58.78–69.74)

76.51 (71.28–81.21)

2.742

80%

69%

  1. Anti-CarP antibodies against carbamylated proteins, ACPA anti-citrullinated protein antibodies, RF rheumatoid factor, LR likelihood ratio, PPV positive predictive value, NPV negative predictive value
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Arthritis Research & Therapy

ISSN: 1478-6362

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