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Table 2 Prevalence of smoking and autoantibodies in RA patients from three different early arthritis cohorts

From: Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study

 

NOAR

EAC

BARFOT

RA patients, n

678

769

795

Ever smokers

432 (64)

415 (54)

471 (59)

Anti-CarP-positive

182 (27)

349 (45)

279 (35)

Anti-CCP2-positive

247 (36)

404 (53)

456 (57)

RF-positive

277 (41)

442 (58)

448 (56)

Anti-CCP2RFAnti-CarP

292 (43)

242 (32)

263 (33)

Anti-CCP2+RFAnti-CarP

51 (8)

20 (3)

45 (6)

Anti-CCP2RF+Anti-CarP

76 (11)

71 (9)

59 (7)

Anti-CCP2RFAnti-CarP+

40 (6)

38 (5)

6 (1)

Anti-CCP2+RF+Anti-CarP

73 (11)

87 (11)

149 (19)

Anti-CCP2+RFAnti-CarP+

15 (2)

27 (4)

33 (4)

Anti-CCP2RF+Anti-CarP+

20 (3)

14 (2)

11 (1)

Anti-CCP2+RF+Anti-CarP+

107 (16)

270 (35)

229 (29)

  1. Data presented as n (%) unless otherwise stated
  2. anti-CarP anti-carbamylated protein antibodies, anti-CCP2 anti-cyclic citrullinated peptide antibodies, BARFOT Better Anti‐Rheumatic Farmaco-Therapy, EAC Early Arthritis Clinic, NOAR Norfolk Arthritis Register, RA rheumatoid arthritis, RF rheumatoid factor