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Table 2 Correlation between the Dysbiosis Index Score and laboratory markers of inflammation, and disease characteristics, respectively

From: Intestinal dysbiosis is common in systemic sclerosis and associated with gastrointestinal and extraintestinal features of disease

 

n

Spearman’s correlation coefficient (rs)

p value

Laboratory markers of inflammation

 C-reactive protein

98

0.35

<0.001

 Haptoglobin

98

0.34

<0.001

 Orosomucoid

98

0.39

<0.001

 α1-antitrypsin

98

0.27

0.007

 Erythrocyte sedimentation rate

98

0.16

0.156

 IgA

98

0.13

0.266

 IgM

98

−0.05

0.654

 IgG

98

−0.05

0.632

 Faecal calprotectin

83

0.38

<0.001

Disease characteristics

 Years since onset of RP

94

−0.07

0.501

 Years since the first non-RP symptom

89

0.09

0.383

 Patient’s age at dysbiosis analysis

98

0.08

0.413

 modified Rodnan skin score

98

0.05

0.659

 Dysmotility of oesophagus

97

0.31

0.002

  1. Ig immunoglobulin, RP Raynaud’s phenomenon