Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 3 Composition of each latent class

From: Discordant inflammation and pain in early and established rheumatoid arthritis: Latent Class Analysis of Early Rheumatoid Arthritis Network and British Society for Rheumatology Biologics Register data

  ERAN BSRBR TNF inhibitor cohort BSRBR non-biologic cohort
Concordant/discordant Con Con Con Dis Dis Con Con Dis Dis Con Con Dis Dis
Descriptor Mild Moderate Severe Better patient-reported Worse patient-reported Moderate Severe Better patient-reported Worse patient-reported Mild Moderate Better patient-reported Worse patient-reported
Number of subjects 220 329 86 91 102 1544 2117 2289 3955 476 1308 248 549
Percentage of total 26% 38% 10% 11% 12% 16% 21% 23% 40% 18% 51% 10% 21%
ESR 22 (19) 25 (18) 42 (29) 40 (26) 44 (29) 42 (27) 52 (31) 39 (26) 49 (29) 27 (21) 33 (23) 44 (28) 38 (26)
SJC 3 (3) 4 (3) 12 (6) 14 (5) 7 (4) 9 (5) 15 (6) 14 (6) 9 (5) 4 (4) 5 (3) 16 (5) 6 (4)
TJC 2 (3) 5 (4) 22 (4) 11 (5) 9 (5) 9 (4) 23 (4) 21 (4) 11 (4) 4 (4) 7 (5) 20 (6) 11 (6)
VAS 20 (15) 44 (20) 66 (20) 50 (20) 73 (16) 57 (20) 84 (15) 69 (19) 74 (18) 34 (21) 51 (21) 72 (18) 69 (16)
BP 46 (6) 31 (7) 24 (6) 32 (6) 22 (5) 34 (7) 20 (4) 27 (6) 23 (5) 43 (6) 31 (5) 27 (7) 23 (5)
VT 52 (9) 40 (8) 33 (8) 46 (8) 30 (8) 45 (9) 25 (6) 39 (9) 30 (7) 51 (7) 39 (7) 36 (9) 28 (6)
MH 55 (7) 45 (9) 39 (9) 52 (8) 32 (10) 50 (9) 32 (10) 46 (9) 38 (10) 56 (7) 47 (9) 43 (10) 32 (9)
Probability of membership of latent class
  > 80% probability 89% 73% 78% 57% 70% 66% 65% 53% 66% 74% 74% 77% 63%
  > 95% probability 71% 40% 56% 30% 41% 40% 37% 22% 38% 51% 36% 59% 38%
  1. Baseline variables used in latent class analysis are summarised to describe composition of each latent class identified within each cohort. The number of participants and the mean (SD) of each variable are shown. The percentage of cases allocated to each latent class is shown for those with a probability of membership in that class >80% or >95%
  2. Abbreviations: BSRBR British Society for Rheumatology Biologics Registers, Dis Discordant, Con Concordant, ESR Erythrocyte sedimentation rate, SJC Swollen joint count, TJC Tender joint count, VAS Visual analogue scale for general health, BP Short Form Health Survey bodily pain, VT Short Form Health Survey vitality, MH Short Form Health Survey mental health, TNF Tumour necrosis factor