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Table 4 Baseline characteristics of the latent classes

From: Discordant inflammation and pain in early and established rheumatoid arthritis: Latent Class Analysis of Early Rheumatoid Arthritis Network and British Society for Rheumatology Biologics Register data

 

ERAN

BSRBR TNF inhibitor cohort

BSRBR control cohort

Concordant/Discordant

Con

Con

Con

Dis

Dis

Heterogeneity

Con

Con

Dis

Dis

Heterogeneity

Con

Con

Dis

Dis

Heterogeneity

Descriptor

Mild

Moderate

Severe

Better patient-reported

Worse patient-reported

 

Moderate

Severe

Better patient-reported

Worse patient-reported

 

Mild

Moderate

Better patient-reported

Worse patient-reported

 

Age

58 (13)

56 (14)

55 (14)

58 (13)

57 (13)

 

56 (13)

56 (12)

57 (14)

56 (12)

*

60 (12)

61 912)

59 (12)

59 (12)

*

Female

60%

68%

65%

66%

81%

*

72%

79%

75%

77%

*

69%

73%

71%

77%

*

DAS28

3.2 (1.1)

4.3 (1.0)

6.9 (0.8)

6.0 (0.7)

5.7 (0.8)

*

5.6 (0.9)

7.5 (0.7)

7.0 (0.7)

6.2 (0.7)

*

4.1 (1.1)

4.9 (1.0)

7.0 (0.8)

5.7 (1.0)

*

HAQ

0.4 (0.5)

1.1 (0.6)

1.8 (0.6)

1.3 (0.6)

1.8 (0.7)

*

2.0 (0.6)

2.0 (0.6)

2.1 (0.6)

2.0 (0.6)

 

0.7 (0.6)

1.5 (0.6)

1.8 (0.6)

2.1 (0.5)

*

  1. Clinical variables not used in the latent class analysis are compared between identified latent classes. Mean (SD) or percentage data are presented
  2. Abbreviations: BSRBR, British Society for Rheumatology Biologics Registers, DAS28 28-joint Disease Activity Score, ERAN Early Rheumatoid Arthritis Network, HAQ Health Assessment Questionnaire, TNF Tumour necrosis factor, Dis Discordant, Con Concordant
  3. *p < 0.05 from one-way analysis of variance for heterogeneity between latent classes within one cohort