Efficacy and safety of adult human bone marrow-derived, cultured, pooled, allogeneic mesenchymal stromal cells (Stempeucel®): preclinical and clinical trial in osteoarthritis of the knee joint

Table 2 Animal grouping and sacrifice schedule

Group		Animals sacrificed (no of rats)*
Group		4 weeks	8 weeks	12 weeks
Group 1	Sham control	2	2	2
Group 2	Vehicle control	3	6	6
Group 3	Hyaluronic acid (HA)	3	6	6
Group 4	Stempeucel® low dose + HA (6 × 10⁵ cells/joint)	3	6	6
Group 5	Stempeucel® high dose + HA (1.3 × 10⁶ cells/joint)	3	6	6

*Number of animals sacrificed at each time point after Stempeucel® administration

ISSN: 1478-6362