Table 3 Logistic regression analysis of serum biomarkers and fatty lesion development visualized by magnetic resonance imaging
Fatty lesion development, odds ratio (95% confidence interval); p value | ||
|---|---|---|
Serum biomarker, time | Week 14 (n = 125) | Week 104 (n = 117) |
Leptin | ||
Baseline | 0.92 (0.87–0.98); p = 0.005 | 0.86 (0.78–0.95); p = 0.004 |
C3 | ||
Baseline | 0.13 (0.04–0.44); p = 0.001 | 0.15 (0.04–0.61); p = 0.008 |
TIMP-1 | ||
Baseline | 1.02 (1.01–1.03); p = 0.005 | 1.02 (1.01–1.04); p = 0.001 |
Change from baseline to week 14 | 0.98 (0.97–1.00); p = 0.030 | 0.96 (0.94–0.98); p = 0.000 |